Sequence information
Variant position: 434 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 778 The length of the canonical sequence.
Location on the sequence:
YDDKQERQSLGESPRTLSPT
P SAEGYQDVRDRMIHRSTSQG
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human YDDKQERQSLGESPRTLSPTP SAEGYQDVRDRMIHRSTSQG
Mouse YEDKQERQSLGESPRTLSPTP SAEGYQDVRDRMIHRSTSQG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
1 – 778
Actin-binding LIM protein 1
Modified residue
422 – 422
Phosphoserine
Modified residue
426 – 426
Phosphoserine
Modified residue
431 – 431
Phosphoserine
Modified residue
433 – 433
Phosphothreonine
Modified residue
435 – 435
Phosphoserine
Modified residue
439 – 439
Phosphotyrosine
Modified residue
452 – 452
Phosphoserine
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.