Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q99459: Variant p.Tyr459Cys

Cell division cycle 5-like protein
Gene: CDC5L
Feedback?
Variant information Variant position: help 459
Type of variant: help LB/B
Residue change: help From Tyrosine (Y) to Cysteine (C) at position 459 (Y459C, p.Tyr459Cys).
Physico-chemical properties: help Change from large size and aromatic (Y) to medium size and polar (C)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 459
Protein sequence length: help 802
Location on the sequence: help PGRTPLRDKLNINPEDGMAD Y SDPSYVKQMERESREHLRLG
Residue conservation: help 
Human                         PGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLG

Mouse                         PGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLG

Rat                           PGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLG

Bovine                        PGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLG

Slime mold                    PTQHNKKQSLNDSNEFAIED-------KFKRQQGKNQLLSN
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 802 Cell division cycle 5-like protein
Region 260 – 606 Interaction with PPP1R8
Modified residue 442 – 442 Phosphothreonine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.