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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q14956: Variant p.Ser538Arg

Transmembrane glycoprotein NMB
Gene: GPNMB
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Variant information Variant position: help 538
Type of variant: help LB/B
Residue change: help From Serine (S) to Arginine (R) at position 538 (S538R, p.Ser538Arg).
Physico-chemical properties: help Change from small size and polar (S) to large size and basic (R)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 538
Protein sequence length: help 572
Location on the sequence: help VYKKHKEYNPIENSPGNVVR S KGLSVFLNRAKAVFFPGNQE
Residue conservation: help 
Human                         VYKKHKEYNPIENSPGNVVRSKGLSVFLNRAKAVFFPGNQE

Mouse                         LYKKHKAYKPIGNCPRNTVKGKGLSVLLSHAKAPFFRGDQE

Rat                           LYKKHKTYKPIGNCTRNVVKGKGLSVFLSHAKAPFSRGDRE
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 23 – 572 Transmembrane glycoprotein NMB
Topological domain 520 – 572 Cytoplasmic
Modified residue 542 – 542 Phosphoserine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.