Variant position: 22 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 400 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ATLLLLLG---VLVVSPDALGST TAV-QTPTSGEPLVSTSEPLSS
Mouse LHLLLLFGACWVQVASPDSLQRT TMLPSTPHITAPSTSEAQ
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
20 – 400 Leukosialin
20 – 253 Extracellular
21 – 224 Disordered
21 – 21 O-linked (GalNAc...) threonine
22 – 22 O-linked (GalNAc...) threonine
26 – 26 O-linked (GalNAc...) threonine
28 – 28 O-linked (GalNAc...) threonine
29 – 29 O-linked (GalNAc...) serine
35 – 35 O-linked (GalNAc...) serine
36 – 36 O-linked (GalNAc...) threonine
37 – 37 O-linked (GalNAc...) serine
41 – 41 O-linked (GalNAc...) serine
42 – 42 O-linked (GalNAc...) serine
No reference for the current variant in UniProtKB/Swiss-Prot.
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.