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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q08752: Variant p.Asp196Val

Peptidyl-prolyl cis-trans isomerase D
Gene: PPID
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Variant information Variant position: help 196
Type of variant: help LB/B
Residue change: help From Aspartate (D) to Valine (V) at position 196 (D196V, p.Asp196Val).
Physico-chemical properties: help Change from medium size and acidic (D) to medium size and hydrophobic (V)
BLOSUM score: help -3
Other resources: help


Sequence information Variant position: help 196
Protein sequence length: help 370
Location on the sequence: help CVIAECGELKEGDDGGIFPK D GSGDSHPDFPEDADIDLKDV
Residue conservation: help 
Human                         CVIAECGELKEG----DDGGIFPKDGSGDSHPD-FPEDADIDLKDV

Mouse                         CVIAECGELKEG----DDWGIFPKDGSGDSHPD-FPEDADI

Rat                           CVIAECGELKEG----DEWGIFPKDGSGDSHPD-FPEDADI

Bovine                        CVIAECGELKEG----DDWGIFPKDGSGDSHPD-FPEDADV

Slime mold                    CVIEDCGQL--------------------------------

Baker's yeast                 VKIDDCGVLPDDYQVPENAEATPTDEYGDNYEDVLKQDEKV

Fission yeast                 VVIEECGTCTK-----DQIEAPKPDVTGDSLEE-FPDDYEG
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 2 – 370 Peptidyl-prolyl cis-trans isomerase D
Region 185 – 215 Chaperone activity
Modified residue 198 – 198 Phosphoserine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.