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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O60259: Variant p.Val154Ile

Kallikrein-8
Gene: KLK8
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Variant information Variant position: help 154
Type of variant: help LB/B
Residue change: help From Valine (V) to Isoleucine (I) at position 154 (V154I, p.Val154Ile).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 3
Other resources: help


Sequence information Variant position: help 154
Protein sequence length: help 260
Location on the sequence: help SKVKPISLADHCTQPGQKCT V SGWGTVTSPRENFPDTLNCA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 33 – 260 Kallikrein-8
Domain 33 – 257 Peptidase S1
Disulfide bond 39 – 173
Disulfide bond 145 – 246
Disulfide bond 152 – 218
Alternative sequence 24 – 164 Missing. In isoform 3.
Alternative sequence 33 – 260 Missing. In isoform 4.
Beta strand 151 – 158



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.