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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P05120: Variant p.Gly374Ala

Plasminogen activator inhibitor 2
Gene: SERPINB2
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Variant information Variant position: help 374
Type of variant: help LB/B
Residue change: help From Glycine (G) to Alanine (A) at position 374 (G374A, p.Gly374Ala).
Physico-chemical properties: help Change from glycine (G) to small size and hydrophobic (A)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 374
Protein sequence length: help 415
Location on the sequence: help VFHQAMVDVNEEGTEAAAGT G GVMTGRTGHGGPQFVADHPF
Residue conservation: help 
Human                         VFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVADHPF

Mouse                         VFHQASVDVTEEGTVAAGGTGAVMTGRTGHGGPQFVADHPF

Rat                           VFHQATVDVNEEGTVAAGGTGAVMTGRTGHGGPQFVADHPF
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 415 Plasminogen activator inhibitor 2
Disulfide bond 5 – 405
Beta strand 368 – 379



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.