Variant position: 97 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 568 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GSQTLRVEKVPSFETA-----EGIG TELKAPLKQEPLQVRVKAVLK
Mouse GSQTPKADKVPSLTQT----VENIG AELKAPLKQDPLQVRV
Xenopus laevis GSKGTSAASSPEKSMA---GLDPSK PEQKSTFPPDPIQVKV
Zebrafish SPTRPEEPKTTEKAQAAQPAAKGAG SKPQGLTKAESIQVKV
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 568 Zinc transporter 9
The novel human HUEL (C4orf1) gene maps to chromosome 4p12-p13 and encodes a nuclear protein containing the nuclear receptor interaction motif.
Sim D.L.C.; Chow V.T.K.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; SUBCELLULAR LOCATION; TISSUE SPECIFICITY; VARIANTS VAL-50 AND ALA-97;
A human HUEL (C4orf1) isoform play the role in spermatogenesis.
Xu Z.Y.; Huang X.Y.; Xu M.; Yin L.L.; Lu L.; Li J.M.; Zhou Z.M.; Sha J.H.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; VARIANTS VAL-50 AND ALA-97;
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS VAL-50 AND ALA-97;
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