Variant position: 104 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 123 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human MDAGLQAWQLRQQKLQEEQ-R KQENALKPKGASLKSPLPSQ
Mouse MDAGIQAWKLRQQKLQEE--R KKEHDLKPKGTLLRSPLPN
Bovine MDAGLQAWQLRQQEKLQEEKR KQQNALKPKGVLLQNPGPS
Xenopus laevis MDQGMTNWHKKQQEMKAEQLQ KEISKLKSKASPNKTTNT-
Drosophila LEFAKQRHERLKANAESEKQR LIRSKLKPKGHFLLKK---
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
24 – 123 39S ribosomal protein L52, mitochondrial
99 – 123 Disordered
88 – 123 Missing. In isoform 4.
No reference for the current variant in UniProtKB/Swiss-Prot.
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