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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P35226: Variant p.Cys18Tyr

Polycomb complex protein BMI-1
Gene: BMI1
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Variant information Variant position: help 18
Type of variant: help LB/B
Residue change: help From Cysteine (C) to Tyrosine (Y) at position 18 (C18Y, p.Cys18Tyr).
Physico-chemical properties: help Change from medium size and polar (C) to large size and aromatic (Y)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 18
Protein sequence length: help 326
Location on the sequence: help MHRTTRIKITELNPHLM C VLCGGYFIDATTIIECLHSF
Residue conservation: help 
Human                         MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSF

Mouse                         MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSF

Bovine                        MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSF

Cat                           MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSF

Chicken                       MHRTTRIKITELNPHLMCVLCGGYFIDATTIIECLHSF
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 326 Polycomb complex protein BMI-1
Zinc finger 18 – 57 RING-type



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.