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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P49221: Variant p.Val409Ile

Protein-glutamine gamma-glutamyltransferase 4
Gene: TGM4
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Variant information Variant position: help 409
Type of variant: help LB/B
Residue change: help From Valine (V) to Isoleucine (I) at position 409 (V409I, p.Val409Ile).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 3
Other resources: help


Sequence information Variant position: help 409
Protein sequence length: help 684
Location on the sequence: help VNGDRLIWLVKMVNGQEELH V ISMETTSIGKNISTKAVGQD
Residue conservation: help 
Human                         VNGDRLIWLVKMVNGQEELHVISMETTSIGKNISTKAVGQD

Mouse                         VNGDKFIWLVKQNQEREKNILIAVETASLGKKISTKMVGEN

Rat                           VNGDKYIWLVKQNQEREKNVLIAVETASIGKNISTKMVGEN
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 684 Protein-glutamine gamma-glutamyltransferase 4
Binding site 390 – 390
Binding site 392 – 392



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.