Variant position: 135 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 660 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human CNSAMGISQ-MLKTKEQKVNP REIAENITKHLPDN-ECIEKVE
Mouse CNSAMGISQ-MLKAKEQKVSP REIAENITKHLPNN-KYIDK
Rat CNSAMGISQ-MLKAKEQKVSP REIAENITKHLPNN-EYIDR
Bovine CNSAMGICQ-MLKTKEQKVNP REIAENIVKHLPDN-EYIEK
Chicken CNSAMGITQILLKTKEQKVSP REIAEKITKHIPAN-ECIEK
Xenopus tropicalis CNSAMAITQ-MLKAMNQKVSP REIADKIVKNIPTN-ELVEK
Caenorhabditis elegans CNSAMPIAA-KLKANKINKRP GDVAKEIQAKLPTKIDFVEK
Drosophila CNNAMGLSK-KLKEKGINKAP RDIATELKGHCPAS-PIIEK
Slime mold ---AVPIPK-LNKFKKLVGKP DQLAIDFASKIQLN-DCIQG
Baker's yeast ---LIPIPR--LRIKGAN--P KDLAVQWAEKFPCG-DFLEK
Fission yeast ---NLPVPR--LRVKGK---P QELAQKWAEAFP-K-DLVE-
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 660 Arginine--tRNA ligase, cytoplasmic
134 – 143
No reference for the current variant in UniProtKB/Swiss-Prot.
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