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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q8WTR7: Variant p.Thr654Ile

Zinc finger protein 473
Gene: ZNF473
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Variant information Variant position: help 654
Type of variant: help LB/B
Residue change: help From Threonine (T) to Isoleucine (I) at position 654 (T654I, p.Thr654Ile).
Physico-chemical properties: help Change from medium size and polar (T) to medium size and hydrophobic (I)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 654
Protein sequence length: help 871
Location on the sequence: help IKLQSFHTKEHPFKCNECGK T FSHSAHLSKHQLIHAGENPF
Residue conservation: help 
Human                         IKLQSFHTKEHPFKCNECGKTFSHSAHLSKHQLIHAGENPF

Mouse                         SEHHP-SQREPSFKCDIYNRAFKQRAHLSKHQLIHITEKPF
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 871 Zinc finger protein 473
Zinc finger 646 – 668 C2H2-type 13
Cross 635 – 635 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
Beta strand 654 – 657



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.