Variant position: 127 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 141 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human GKLDRGAASRFVKNALWEPK SKNAS--KVANKGKSKS------
Mouse AKLDRGAASRFVKNALWEPK AKSTP--KVANKGKS
Bovine GKLDRGAASRFVKNALWEPK PKNAS--KVANKGKS
Chicken SKLDKGAASRFVRNALWEPN PENGQ---TPAKAKK
Xenopus laevis ARLDKGAARRFIKHALCDPT SEEAPPAKMDCKAKK
Zebrafish AHIDKEAASRFVRNALWDAD DKKRK-DKTEHQQKG
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 141 Nuclear nucleic acid-binding protein C1D
100 – 141 Interaction with NCOR1 and NCOR2
119 – 119 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
126 – 126 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
132 – 132 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)
No reference for the current variant in UniProtKB/Swiss-Prot.
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