Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q13421: Variant p.Gly497Glu

Mesothelin
Gene: MSLN
Feedback?
Variant information Variant position: help 497
Type of variant: help LB/B
Residue change: help From Glycine (G) to Glutamate (E) at position 497 (G497E, p.Gly497Glu).
Physico-chemical properties: help Change from glycine (G) to medium size and acidic (E)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 497
Protein sequence length: help 630
Location on the sequence: help DPRQLDVLYPKARLAFQNMN G SEYFVKIQSFLGGAPTEDLK
Residue conservation: help 
Human                         DPRQLDVLYPKARLAFQNMNGSEYFVKIQSFLGGAPTEDLK

Mouse                         SQRHLGLLYQKACSAFQNVSGLEYFEKIKTFLGGASVKDLR

Rat                           SQRHLGILYQKACSAFQNVSGLEYFEKIRTFLGGASREDLR
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 37 – 606 Mesothelin
Chain 296 – 606 Mesothelin, cleaved form
Glycosylation 496 – 496 N-linked (GlcNAc...) asparagine
Helix 497 – 504



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.