Variant position: 374 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 416 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VMKFVPRYSLVLELSDSGAF RRSLHDPDGLVATYISEVHEH
Mouse VMKFVPRYSLVLEVSDSGAF RRSLHDPDGQVVTYVSEAHEH
Rat VMKFVPRYSLVLEVSDSGAF RRSLHDPDGQVVTYVSEAHEH
Bovine VMKFVPRYSLVLELSDSGTF LRSLHDPEGQVVTYVSEAHEH
Chicken VTKLLPKRSLVVELSETGSY RRSFHDPTGLTVPYVSEAHEH
Zebrafish LLKFVPRYSLVVELQSDGTC VRSFHDPQGLVSAYSSEAHEY
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 416 Adipocyte plasma membrane-associated protein
62 – 416 Extracellular
290 – 416 Missing. In isoform 2.
Localization and characterization of the novel protein encoded by C20orf3.
Ilhan A.; Gartner W.; Nabokikh A.; Daneva T.; Majdic O.; Cohen G.; Boehmig G.A.; Base W.; Hoerl W.H.; Wagner L.;
Biochem. J. 414:485-495(2008)
Cited for: FUNCTION; SUBCELLULAR LOCATION; TISSUE SPECIFICITY; VARIANTS GLN-282 AND TRP-374;
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.