Variant position: 144 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 594 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human PNGSFLTCFMYLPVPWNLDS IIQFGLNDTDTCQDGWIYPDA
Mouse PNGSFLTCLMYIPVPWDLDS IIHFGLNYTETCKFGWIYPFA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 594 Solute carrier family 22 member 14
92 – 184 Extracellular
125 – 125 N-linked (GlcNAc...) asparagine
150 – 150 N-linked (GlcNAc...) asparagine
Molecular cloning, mapping, and characterization of two novel human genes, ORCTL3 and ORCTL4, bearing homology to organic-cation transporters.
Nishiwaki T.; Daigo Y.; Tamari M.; Fujii Y.; Nakamura Y.;
Cytogenet. Cell Genet. 83:251-255(1998)
Cited for: NUCLEOTIDE SEQUENCE [MRNA]; TISSUE SPECIFICITY; VARIANTS THR-144; MET-284 AND GLY-292;
Characterization of a 1200-kb genomic segment of chromosome 3p22-p21.3.
Daigo Y.; Isomura M.; Nishiwaki T.; Tamari M.; Ishikawa S.; Kai M.; Takeuchi K.; Yamane Y.; Hayashi R.; Minami M.; Fujino M.A.; Hojo Y.; Uchiyama I.; Takagi T.; Nakamura Y.;
DNA Res. 6:37-44(1999)
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; VARIANTS THR-144; MET-284 AND GLY-292;
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.