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UniProtKB/Swiss-Prot O15397: Variant p.Ile640Val

Importin-8
Gene: IPO8
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Variant information Variant position: help 640
Type of variant: help LB/B
Residue change: help From Isoleucine (I) to Valine (V) at position 640 (I640V, p.Ile640Val).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 3
Other resources: help


Sequence information Variant position: help 640
Protein sequence length: help 1037
Location on the sequence: help TVVEDHKEITQQLENICLRI I DLVLQKHVIEFYEEILSLAY
Residue conservation: help 
Human                         TVVEDHKEITQQLENICLRIIDLVLQKHVI---EFYEEILSLAY

Mouse                         TVVEDHPEIIQQLENICLRIIDLVLQKHVI---EFYEEILS

Zebrafish                     TVMGDRKEISQQLEGICLQVIGLVLQKPIIGMAEFYEEILS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1037 Importin-8



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.