Variant position: 167 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 956 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human ING---QREDTGDQQGLLKAIQN DKLAFPGETLSDIPCKTEEEG
Mouse VEGAAKQQEHSAAELCLL----- -------ETPSDITCHME
Bovine ING---VPDKAGDDRGLPKARQK DELASPEEALSEVPCKTE
Chicken -NG---MLGKDMNKLSCLNSTQN SQ--TDDSMQTDVPCEAI
Zebrafish ------QPAPPIAATCPLSEEKT KT--SEGTTEPTIPLTEE
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 956 Chromatin assembly factor 1 subunit A
1 – 314 Binds to CBX1 chromo shadow domain
182 – 182 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1); alternate
182 – 182 Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate
No reference for the current variant in UniProtKB/Swiss-Prot.
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