Variant position: 923 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 956 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human DTEEEEEEEGDCMIV------DVPDA AEVQAPCGAASGAGGGVGVDT
Mouse DTEEDEEDDTDCMII------DVPDV ---------------
Bovine DTEEEDDDEGDCVIM------DISDV GDIQAPCGTTSGAGG
Chicken DTEEDEDDD-DCMIV------DVQPC KDSTLTVTETAPESR
Zebrafish DTEDDEDDD--CIIIGEQSGSSEQDI NTSLPQTDRETEPMD
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 956 Chromatin assembly factor 1 subunit A
660 – 956 Binds to p60
750 – 956 Missing. In isoform 2.
772 – 944 Missing. In isoform 3.
Genomic sequence and expression analyses of human chromatin assembly factor 1 p150 gene.
Dong H.; Lin W.; Zhang C.-K.; Xiong H.; Fu G.; Jin W.-R.; Chen R.; Chen Z.; Qi Z.-T.; Huang G.M.;
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]; ALTERNATIVE SPLICING (ISOFORMS 1; 2 AND 3); VARIANT VAL-923;
The p150 and p60 subunits of chromatin assembly factor I: a molecular link between newly synthesized histones and DNA replication.
Kaufman P.D.; Kobayashi R.; Kessler N.; Stillman B.;
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-956 (ISOFORM 1); VARIANT VAL-923;
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