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UniProtKB/Swiss-Prot Q7Z3Y8: Variant p.Ala284Thr

Keratin, type I cytoskeletal 27
Gene: KRT27
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Variant information Variant position: help 284
Type of variant: help LB/B
Residue change: help From Alanine (A) to Threonine (T) at position 284 (A284T, p.Ala284Thr).
Physico-chemical properties: help Change from small size and hydrophobic (A) to medium size and polar (T)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 284
Protein sequence length: help 459
Location on the sequence: help YEALAEQNRRDAEAWFNEKS A SLQQQISDDAGATTSARNEL
Residue conservation: help 
Human                         YEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNEL

Mouse                         YEALAEQNRRDAEAWFQEKSASLQQQISDDAGATTSARNEL

Rat                           YEALAEQNRRDAEAWFQEKSASLQQQISDDAGATTSARNEL

Bovine                        YEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNEL

Goat                          YEALAEQNRRDAEAWFNEKSASLQQQISDDAGATTSARNEL
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 459 Keratin, type I cytoskeletal 27
Domain 84 – 399 IF rod
Region 257 – 395 Coil 2



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.