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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O95049: Variant p.Met898Thr

Tight junction protein ZO-3
Gene: TJP3
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Variant information Variant position: help 898
Type of variant: help LB/B
Residue change: help From Methionine (M) to Threonine (T) at position 898 (M898T, p.Met898Thr).
Physico-chemical properties: help Change from medium size and hydrophobic (M) to medium size and polar (T)
BLOSUM score: help -1
Other resources: help


Sequence information Variant position: help 898
Protein sequence length: help 919
Location on the sequence: help GQWRQDSMRTYEREALKKKF M RVHDAESSDEDGYDWGPATD
Residue conservation: help 
Human                         GQWRQDSMRTYEREALKKKFMRVHDAESSDEDGYDWGPATD

                              SQGRQDSMRTYGQEALKKKFTRARDVESSDEDGYDWGPATD

Mouse                         DQRRQDSMRTYKHEALRKKFTRARDVESSDDEGYDWGPATD
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 919 Tight junction protein ZO-3
Modified residue 905 – 905 Phosphoserine
Modified residue 906 – 906 Phosphoserine



Literature citations
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3); VARIANT THR-898;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.