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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q96RS0: Variant p.Thr595Ala

Trimethylguanosine synthase
Gene: TGS1
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Variant information Variant position: help 595
Type of variant: help LB/B
Residue change: help From Threonine (T) to Alanine (A) at position 595 (T595A, p.Thr595Ala).
Physico-chemical properties: help Change from medium size and polar (T) to small size and hydrophobic (A)
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 595
Protein sequence length: help 853
Location on the sequence: help SVSSAGELETENYERDSLLA T VPDEQDCVTQEVPDSRQAET
Residue conservation: help 
Human                         SVSSAGELETENYERDSLLATVPDEQDCVTQEVPDSRQAET

Mouse                         IISSATELEAEKSEVGSLVATVPE--NCSTEEIPNSPHAET

Rat                           TISSASELEAEKSEGGSLVAAVPE--NCSTEGVANSPRAEA

Baker's yeast                 -----------------------------------------

Fission yeast                 ---------------------VPK-----------------
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 853 Trimethylguanosine synthase
Region 527 – 632 Disordered
Modified residue 578 – 578 Phosphoserine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.