UniProtKB/SwissProt variant VAR

Z-DNA-binding protein 1
Gene: ZBP1
Feedback?

Variant information Variant position:

70
Type of variant:

LB/B
Residue change:

From Glycine (G) to Arginine (R) at position 70 (G70R, p.Gly70Arg).
Physico-chemical properties:

Change from glycine (G) to large size and basic (R)
BLOSUM score:

-2
Other resources:

Variant rs34964609 [ dbSNP | Ensembl ]

Sequence information Variant position:

70
Protein sequence length:

429
Location on the sequence:

YRMKKELKVSLTSPATWCLG G TDPEGEGPAELALSSPAERP
Residue conservation:

Human                         YRMKKELKVSLTSPATWCLGGTDPEGEGPAELALSSPAERP

Mouse                         YRLKKEDRVSSPEPATWSIGGA-ASGDG-------------

Rat                           YRLKKEGRVSSPAPATWSLGGDGASGDG-------------

Sequence annotation in neighborhood:

Type	Positions	Description
Chain	1 – 429	Z-DNA-binding protein 1
Domain	8 – 70	Z-binding 1
Region	68 – 107	Disordered
Alternative sequence	12 – 86	Missing. In isoform 7.
Beta strand	65 – 72

Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.

Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9H171: Variant p.Gly70Arg