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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P42694: Variant p.Val74Met

Probable helicase with zinc finger domain
Gene: HELZ
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Variant information Variant position: help 74
Type of variant: help LB/B
Residue change: help From Valine (V) to Methionine (M) at position 74 (V74M, p.Val74Met).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 74
Protein sequence length: help 1942
Location on the sequence: help RIKIESLLYRIASFLQLKNY V QADEDCRHVLGEGLAKGEDA
Residue conservation: help 
Human                         RIKIESLLYRIASFLQLKNYVQADEDCRHVLGEGLAKGEDA

Mouse                         RIKIESLLYRIASFLQLKNYGQADEDCRHVLGEGLAKGERA

Zebrafish                     LLRTRALLYRIAARLQLKDYDQADEDCKHVFAEELAKGDGS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 1942 Probable helicase with zinc finger domain



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.