Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q9Y2C9: Variant p.His345Tyr

Toll-like receptor 6
Gene: TLR6
Feedback?
Variant information Variant position: help 345
Type of variant: help LB/B
Residue change: help From Histidine (H) to Tyrosine (Y) at position 345 (H345Y, p.His345Tyr).
Physico-chemical properties: help Change from medium size and polar (H) to large size and aromatic (Y)
BLOSUM score: help 2
Other resources: help


Sequence information Variant position: help 345
Protein sequence length: help 796
Location on the sequence: help YTVFSEMNIMMLTISDTPFI H MLCPHAPSTFKFLNFTQNVF
Residue conservation: help 
Human                         YTVFSEMNIMMLTISDTPFIHMLCPHAPSTFKFLNFTQNVF

Mouse                         YSVFAEMNIKMLSISDTPFIHMVCPPSPSSFTFLNFTQNVF

Bovine                        YTVFSEMNILMLTISDTRFIHMLCPQEPSTFKFLNFTQNSF
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 32 – 796 Toll-like receptor 6
Topological domain 32 – 586 Extracellular
Repeat 331 – 354 LRR 12
Glycosylation 359 – 359 N-linked (GlcNAc...) asparagine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.