UniProtKB/SwissProt variant VAR

G protein-regulated inducer of neurite outgrowth 2
Gene: GPRIN2
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Variant information Variant position:

91
Type of variant:

LB/B
Residue change:

From Tryptophan (W) to Arginine (R) at position 91 (W91R, p.Trp91Arg).
Physico-chemical properties:

Change from large size and aromatic (W) to large size and basic (R)
BLOSUM score:

-3
Other resources:

Variant rs3127820 [ dbSNP | Ensembl ]

Sequence information Variant position:

91
Protein sequence length:

458
Location on the sequence:

SMKPARASGPKARPSAGGHW W SSTVGNVSTMGGSDLCRLRA
Residue conservation:

Human                         SMKPARASG----PKARPSAGGHWWSSTVGNVSTMGGSDLCRLRA

Chicken                       CFKHQQSMGKMDEPRAVLQRSHSDLTCSCKQQSYVTHVETS

Sequence annotation in neighborhood:

Type	Positions	Description
Chain	1 – 458	G protein-regulated inducer of neurite outgrowth 2
Region	1 – 94	Disordered

Literature citations
Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
Nagase T.; Ishikawa K.; Miyajima N.; Tanaka A.; Kotani H.; Nomura N.; Ohara O.;
DNA Res. 5:31-39(1998)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS HIS-5; HIS-40; MET-47; ARG-91; GLY-104 AND PRO-400; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS HIS-5; HIS-40; MET-47; ARG-91; GLY-104; ALA-375 AND PRO-400;

Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot O60269: Variant p.Trp91Arg