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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q8IWV8: Variant p.Ala1095Ser

E3 ubiquitin-protein ligase UBR2
Gene: UBR2
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Variant information Variant position: help 1095
Type of variant: help LB/B
Residue change: help From Alanine (A) to Serine (S) at position 1095 (A1095S, p.Ala1095Ser).
Physico-chemical properties: help Change from small size and hydrophobic (A) to small size and polar (S)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 1095
Protein sequence length: help 1755
Location on the sequence: help SAVLDHSPVASDMTLTALGP A QTQVPEQRQFVTCILCQEEQ
Residue conservation: help 
Human                         SAVLDHSPVASDMTLTALGPAQTQVPEQRQFVTCILCQEEQ

Mouse                         SATLDSSPPVSDAALTALGPAQTQVPEPRQFVTCILCQEEQ

Baker's yeast                 SPSLSPTRINAENSSNTINSCCDD--------DCVFCKMPK
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 2 – 1755 E3 ubiquitin-protein ligase UBR2
Binding site 1108 – 1108
Binding site 1111 – 1111
Alternative sequence 440 – 1755 Missing. In isoform 2.
Alternative sequence 1072 – 1755 Missing. In isoform 3.



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.