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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q2WGJ6: Variant p.Arg346Lys

Kelch-like protein 38
Gene: KLHL38
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Variant information Variant position: help 346
Type of variant: help LB/B
Residue change: help From Arginine (R) to Lysine (K) at position 346 (R346K, p.Arg346Lys).
Physico-chemical properties: help Similar physico-chemical property. Both residues are large size and basic.
BLOSUM score: help 2
Other resources: help


Sequence information Variant position: help 346
Protein sequence length: help 581
Location on the sequence: help SAITLHRSIYVLGGMAVSSG R SLVSHNVYIFSLKLNQWRLG
Residue conservation: help 
Human                         SAITLHRSIYVLGGMAVS--SGRSLVSHNVYIFSLKLNQWRLG

Mouse                         SAVTLHRSVYVLGGMTVS--EGKSLISCGVYIFSLKLNQWR

Rat                           SAVTLHRSVYVLGGMAVR--EGKGLISCSVYIFSMKLNQWR

Zebrafish                     AYVCIHSILYVVGGLSLSLVSGDSAVSATVYTLSLKTNQWR
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 581 Kelch-like protein 38
Repeat 334 – 383 Kelch 2



Literature citations
Submission
Mural R.J.; Istrail S.; Sutton G.G.; Florea L.; Halpern A.L.; Mobarry C.M.; Lippert R.; Walenz B.; Shatkay H.; Dew I.; Miller J.R.; Flanigan M.J.; Edwards N.J.; Bolanos R.; Fasulo D.; Halldorsson B.V.; Hannenhalli S.; Turner R.; Yooseph S.; Lu F.; Nusskern D.R.; Shue B.C.; Zheng X.H.; Zhong F.; Delcher A.L.; Huson D.H.; Kravitz S.A.; Mouchard L.; Reinert K.; Remington K.A.; Clark A.G.; Waterman M.S.; Eichler E.E.; Adams M.D.; Hunkapiller M.W.; Myers E.W.; Venter J.C.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]; VARIANTS VAL-334 AND LYS-346; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANTS VAL-334 AND LYS-346;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.