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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot P78325: Variant p.Arg433Cys

Disintegrin and metalloproteinase domain-containing protein 8
Gene: ADAM8
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Variant information Variant position: help 433
Type of variant: help LB/B
Residue change: help From Arginine (R) to Cysteine (C) at position 433 (R433C, p.Arg433Cys).
Physico-chemical properties: help Change from large size and basic (R) to medium size and polar (C)
BLOSUM score: help -3
Other resources: help


Sequence information Variant position: help 433
Protein sequence length: help 824
Location on the sequence: help NLFVERGEQCDCGPPEDCRN R CCNSTTCQLAEGAQCAHGTC
Residue conservation: help 
Human                         NLFVERGEQCDCGPPEDCRNRCCNSTTCQLAEGAQCAHGTC

Mouse                         NLFVEHGEQCDCGTPQDCQNPCCNATTCQLVKGAECASGTC
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 17 – 824 Disintegrin and metalloproteinase domain-containing protein 8
Topological domain 17 – 655 Extracellular
Domain 408 – 494 Disintegrin
Glycosylation 436 – 436 N-linked (GlcNAc...) asparagine



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.