UniProtKB/SwissProt variant VAR

Tryptase alpha/beta-1
Gene: TPSAB1
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Variant information Variant position:

3
Type of variant:

LB/B
Residue change:

From Asparagine (N) to Serine (S) at position 3 (N3S, p.Asn3Ser).
Physico-chemical properties:

Change from medium size and polar (N) to small size and polar (S)
BLOSUM score:

1
Polymorphism:

There are two alleles alpha and beta-I. The sequence shown is that of allele beta-I.
Variant description:

In allele alpha.
Other resources:

Variant rs371929937 [ dbSNP | Ensembl ]

Sequence information Variant position:

3
Protein sequence length:

275
Location on the sequence:

ML N LLLLALPVLASRAYAAPAPG
Residue conservation:

Human                         MLNLLLLALPVLASRAYAAPAPG

Mouse                         MLKLLLLTLPLLSSLVHAAPGP-

Rat                           MLKLLLLTLPLLSSLVHAAPSL-

Sequence annotation in neighborhood:

Type	Positions	Description
Signal peptide	1 – 18

Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.

Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q15661: Variant p.Asn3Ser