Variant position: 98 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 338 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human VLDPRLLVGCAVAVLAVHGA GNLVNTYYDFSKGID-HKKSDD
Mouse VLDPRLLLGCAVAVLAVHGA GNLVNTYYDFSKGID-HKKSD
Rat VLDPRLLLGCAVAVLAVHGA GNLVNTYYDFSKGID-HKKSD
Chicken ALDPRLLVGSAVAVLAVHGA GNLVNTYYDFSKGID-HKKSD
Xenopus tropicalis SLDLLLFVVCAVAVLAVHGA GNLVNTYYDFSKGID-HKKSD
Zebrafish SVDLLLLLVCAVAVLLVHGA GNLVNTYYDFSKGID-HKKSD
Drosophila EFSLATFFLTAFTVVTVHCA GNVVNTYFDFIKGID-KQKAD
Slime mold EFDSIMLSIILVGAVSLQAL GNVVNSFYDCKNGNDTKEKSA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
2 – 338 UbiA prenyltransferase domain-containing protein 1
83 – 103 Helical
A novel UBIAD1 mutation identified in a Chinese family with Schnyder crystalline corneal dystrophy.
Jing Y.; Liu C.; Xu J.; Wang L.;
Mol. Vis. 15:1463-1469(2009)
Cited for: VARIANT SCCD SER-98;
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