Variant position: 201 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 729 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human EKKATHKEKIEKKEKPETKT LAKEQKKAKTAEKSEEKTKKE
Mouse EKTATHKEKLEKKERPETKM MAKEDKKIKTKEKTEEKAKKE
Rat EKKATHKEKLEKKERTETKM AAKEDKKIKTKEKTEEKAKKE
Rabbit EKKATHKEKLEKKEKPETKT VTKEEKKARTKEKIEEKTKKE
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 729 Triadin
69 – 729 Lumenal
117 – 265 Disordered
132 – 265 Basic and acidic residues
168 – 729 Missing. In isoform 3.
Molecular cloning of the cDNA encoding human skeletal muscle triadin and its localisation to chromosome 6q22-6q23.
Taske N.L.; Eyre H.J.; O'Brien R.O.; Sutherland G.R.; Denborough M.A.; Foster P.S.;
Eur. J. Biochem. 233:258-265(1995)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1); VARIANTS VAL-201 AND SER-438;
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2 AND 3); VARIANTS SER-128 AND VAL-201;
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