Variant position: 314 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 466 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human YVPGTTNHDIALLRLHQPVV LTDHVVPLCLPERTFSERTLA
Chimpanzee YIPGTTNHDIALLRLHQPVV LTDHVVPLCLPERAFSERTLA
Mouse YIRGKINHDIALLRLHRPVT FTDYVVPLCLPEKSFSENTLA
Rat YTRGRTDHDIALVRLHRPVT FTDYVVPLCLPERAFSENTLA
Bovine YVPGQTDHDVALLQLAQPVA LGDHVAPLCLPDPDFADQTLA
Rabbit YVPGKTDHDIALLRLLQPAA LTNNVVPLCLPERNFSESTLA
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Recurrent mutations and genotype-phenotype correlations in hereditary factor VII deficiency in Korea.
Kwon M.J.; Yoo K.Y.; Lee K.O.; Kim S.H.; Kim H.J.;
Blood Coagul. Fibrinolysis 22:102-105(2011)
Cited for: VARIANTS FA7D ARG-59 INS; VAL-314; SER-343 AND GLY-389;
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