Variant position: 362 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 763 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human YAAQLAAMQVSPGGKLPGIP QGNLGAAVSPTSIHTDKSTNS
Mouse YAAQLAAMQVSPGGKLLGLP QGNLGAAVSPTSIHTDKSTNS
Rat YAAQLAAMQVSPGGKLLGLP QGNLGAAVSPTSIHTDKSTNS
Xenopus laevis YAAQLAAMQVSPGAKLPGVP QNNLSNSISPSSVHTDKSTSS
Xenopus tropicalis YAAQLAAMQVSPGAKLPGVP PSNLSNAVSPSSIHTDKSTSS
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
1 – 763 Transcription factor SOX-5
359 – 426 Disordered
370 – 370 Phosphoserine
372 – 372 Phosphothreonine
1 – 386 Missing. In isoform 3.
Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis.
Daoud H.; Valdmanis P.N.; Gros-Louis F.; Belzil V.; Spiegelman D.; Henrion E.; Diallo O.; Desjarlais A.; Gauthier J.; Camu W.; Dion P.A.; Rouleau G.A.;
Arch. Neurol. 68:587-593(2011)
Cited for: VARIANT PRO-362;
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