Variant position: 365 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 524 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human HLLDFLGMIFLTMIWAICPR DSLALLCQWIQSKLQEYMFNR
Mouse HLLDFLGMIFLTMIWAICPR DSLAVLGQWIQSKLQEYMFDR
Rat HLLDFLGMIFLTMIWAICPR DSLAVLGQWIQSKLQEYMFDR
Bovine HLLDFLGLIFLTTIWAICPR DSLALLGQWIQSKLQEFLFDR
Zebrafish HVVELLSLVLLTAIWAVCPR DSLAALGHWIQGKLVQFLFDR
Baker's yeast PIYSLLGLVLYTV------- ----TGAHAINNILLDGFLRM
Fission yeast RAVS--CIVFLAA------- ASLDLSGQ-LSHFLLNFGLLL
Resequencing of 29 candidate genes in patients with familial and sporadic amyotrophic lateral sclerosis.
Daoud H.; Valdmanis P.N.; Gros-Louis F.; Belzil V.; Spiegelman D.; Henrion E.; Diallo O.; Desjarlais A.; Gauthier J.; Camu W.; Dion P.A.; Rouleau G.A.;
Arch. Neurol. 68:587-593(2011)
Cited for: VARIANTS TYR-69; LEU-117; GLY-272; LEU-329 AND TYR-365;
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