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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q13200: Variant p.Asn724Tyr

26S proteasome non-ATPase regulatory subunit 2
Gene: PSMD2
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Variant information Variant position: help 724
Type of variant: help LB/B
Residue change: help From Asparagine (N) to Tyrosine (Y) at position 724 (N724Y, p.Asn724Tyr).
Physico-chemical properties: help Change from medium size and polar (N) to large size and aromatic (Y)
BLOSUM score: help -2
Other resources: help


Sequence information Variant position: help 724
Protein sequence length: help 908
Location on the sequence: help LNILDTLSKFSHDADPEVSY N SIFAMGMVGSGTNNARLAAM
Residue conservation: help 
Human                         LNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAM

Mouse                         LNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAM

Rat                           LNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAM

Bovine                        LNILDTLSKFSHDADPEVSYNSIFAMGMVGSGTNNARLAAM

Slime mold                    IAIMDILSKLSHDNDPEVAQGAILSLGLIGAGTNNARIGGM
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 908 26S proteasome non-ATPase regulatory subunit 2
Region 708 – 903 Required for interaction with UBLCP1
Helix 719 – 732



Literature citations
Cloning of human full-length CDSs in BD Creator(TM) system donor vector.
Kalnine N.; Chen X.; Rolfs A.; Halleck A.; Hines L.; Eisenstein S.; Koundinya M.; Raphael J.; Moreira D.; Kelley T.; LaBaer J.; Lin Y.; Phelan M.; Farmer A.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANT TYR-724; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]; VARIANT TYR-724;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.