Variant position: 1670 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 4563 The length of the canonical sequence.
Location on the sequence:
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human DGISTSATTNLKCSLLVLEN ELNAELGLSGASMKLTTNGRF
Mouse DGLSTSATTNLKYSPLLLEN ELNAELGLSGASMKLSTNGRF
Rat DGVSTSATTNLKYSPLLLEN ELNAELGLSGASMKLSTSGRF
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:
Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
28 – 4563 Apolipoprotein B-100
28 – 2179 Apolipoprotein B-48
Analysis of cDNA clones encoding the entire B-26 region of human apolipoprotein B.
Protter A.A.; Hardman D.A.; Sato K.Y.; Schilling J.W.; Yamanaka M.; Hort Y.J.; Hjerrild K.A.; Chen G.C.; Kane J.P.;
Proc. Natl. Acad. Sci. U.S.A. 83:5678-5682(1986)
Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-1670; VARIANTS ILE-98; CYS-1422 AND ASP-1670;
Quantitative detection of single amino acid polymorphisms by targeted proteomics.
Su Z.D.; Sun L.; Yu D.X.; Li R.X.; Li H.X.; Yu Z.J.; Sheng Q.H.; Lin X.; Zeng R.; Wu J.R.;
J. Mol. Cell Biol. 3:309-315(2011)
Cited for: VARIANTS GLU-1218; ASP-1670; ASN-2037; CYS-2564 AND LYS-2566; IDENTIFICATION BY MASS SPECTROMETRY;
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