Expasy logo

UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q92870: Variant p.Arg179Gln

Amyloid beta precursor protein binding family B member 2
Gene: APBB2
Feedback?
Variant information Variant position: help 179
Type of variant: help LB/B
Residue change: help From Arginine (R) to Glutamine (Q) at position 179 (R179Q, p.Arg179Gln).
Physico-chemical properties: help Change from large size and basic (R) to medium size and polar (Q)
BLOSUM score: help 1
Other resources: help


Sequence information Variant position: help 179
Protein sequence length: help 758
Location on the sequence: help KSFLNYYADLETSARELEQN R GNHHGTAEEKSQPVQGQAST
Residue conservation: help
Human                         KSFLNYYADLETSARELEQNRGNHHGTAEEKSQPVQGQAST

Mouse                         KSFLNYYADLETSARELGQNLGPCQGVGEEKAQPGPGQAPV

Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 1 – 758 Amyloid beta precursor protein binding family B member 2
Region 176 – 195 Disordered
Compositional bias 176 – 190 Basic and acidic residues
Modified residue 160 – 160 Phosphoserine
Alternative sequence 1 – 548 Missing. In isoform 3.



Literature citations
Homo sapiens protein coding cDNA.
Totoki Y.; Toyoda A.; Takeda T.; Sakaki Y.; Tanaka A.; Yokoyama S.; Ohara O.; Nagase T.; Kikuno R.F.;
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4); VARIANT GLN-179; The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
The MGC Project Team;
Genome Res. 14:2121-2127(2004)
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2); VARIANT GLN-179;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.