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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q8TAV3: Variant p.Gln482His

Cytochrome P450 2W1
Gene: CYP2W1
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Variant information Variant position: help 482
Type of variant: help LB/B
Residue change: help From Glutamine (Q) to Histidine (H) at position 482 (Q482H, p.Gln482His).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and polar.
BLOSUM score: help 0
Other resources: help


Sequence information Variant position: help 482
Protein sequence length: help 490
Location on the sequence: help VSPASLDTTPARAFTMRPRA Q ALCAVPRP
Residue conservation: help 
Human                         VSPASLDTTPARAFTMRPRAQALCAVPRP

Mouse                         LSPADLDLRPAPAFTMRPPAQTLCVVPRS
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 23 – 490 Cytochrome P450 2W1



Literature citations
CYP2W1 variant alleles in Caucasians and association of the CYP2W1 G541A (Ala181Thr) polymorphism with increased colorectal cancer risk.
Gervasini G.; de Murillo S.G.; Ladero J.M.; Agundez J.A.;
Pharmacogenomics 11:919-925(2010)
Cited for: VARIANTS ALA-58; THR-181; ILE-432; HIS-482 AND LEU-488;
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.