Sequence information
Variant position: 524 The position of the amino-acid change on the UniProtKB canonical protein sequence.
Protein sequence length: 874 The length of the canonical sequence.
Location on the sequence:
NRVFVYCAFLDFSSGEGVWS
N HGCALTRGNLTYSVCRCTHL
The residue change on the sequence. Unless the variant is located at the beginning or at the end of the protein sequence, both residues upstream (20) and downstream (20) of the variant will be shown.
Residue conservation: The multiple alignment of the region surrounding the variant against various orthologous sequences.
Human NRVFVYCAFLDFSSGEGVWSN HGCALTRGNLTYSVCRCTHL
Mouse NRLFLYCAFLNFSSGEGVWSS QGCALTEGNLTYSVCHCTHL
Bovine NRIFLYCAFLDFSSGEGIWSN QGCALTEGNLSYSICRCTHL
Sequence annotation in neighborhood: The regions or sites of interest surrounding the variant. In general the features listed are posttranslational modifications, binding sites, enzyme active sites, local secondary structure or other characteristics reported in the cited references. The "Sequence annotation in neighborhood" lines have a fixed format:Type: the type of sequence feature. Positions: endpoints of the sequence feature. Description: contains additional information about the feature.
Type Positions Description
Chain
26 – 874
Adhesion G-protein coupled receptor D1
Topological domain
26 – 570
Extracellular
Domain
507 – 556
GPS
Glycosylation
533 – 533
N-linked (GlcNAc...) asparagine
Mutagenesis
543 – 543
H -> R. Does not affect membrane trafficking and basal activity.
Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer:
Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.