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UniProtKB/Swiss-Prot variant pages

UniProtKB/Swiss-Prot Q6QNK2: Variant p.Val764Met

Adhesion G-protein coupled receptor D1
Gene: ADGRD1
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Variant information Variant position: help 764
Type of variant: help LB/B
Residue change: help From Valine (V) to Methionine (M) at position 764 (V764M, p.Val764Met).
Physico-chemical properties: help Similar physico-chemical property. Both residues are medium size and hydrophobic.
BLOSUM score: help 1
Variant description: help Reduces cell membrane location; decreases G-protein coupled receptor activity.
Other resources: help


Sequence information Variant position: help 764
Protein sequence length: help 874
Location on the sequence: help DNYKIHGDPSAFKLTAKAVA V LLPILGTSWVFGVLAVNGCA
Residue conservation: help 
Human                         DNYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNGCA

Mouse                         DSYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVSDRA

Bovine                        ENYKIHGDPSAFKLTAKAVAVLLPILGTSWVFGVLAVNNQA
Sequence annotation in neighborhood: help
TypePositionsDescription
Chain 26 – 874 Adhesion G-protein coupled receptor D1
Transmembrane 761 – 781 Helical; Name=6



Literature citations
No reference for the current variant in UniProtKB/Swiss-Prot.
Disclaimer: Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. They are not in any way intended to be used as a substitute for professional medical advice, diagnostic, treatment or care.