Temperatures can get cold. And living organisms have to find ways of keeping themselves warm. Humans use clothes. Polar bears grow fur. Whales are lined with blubber. And many animals avoid the cold by migrating to warmer parts of the planet. But for cold-blooded animals - such as fish - things are sometimes more complicated. Especially when they live in waters which are ice-cold, on a seasonal basis or not. The formation of ice in an organism is dangerous because it can damage cells irreversibly. To solve this problem, Nature thought up an antifreeze system which hinders ice formation: antifreeze proteins. There are all sorts of antifreeze proteins but one is particularly special - Maxi - and keeps fish alive in waters as cold as - 1.9 °C. As its name suggests, it is much larger than the other antifreeze proteins known to date, but it also behaves very differently. What is more, its 3D structure has shed a very different light on the way the core of a protein is formed.
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« Globin and Poietin set out to save Lily's life. But time is running short and they can't find the marrow... Here is the tale of their courage, fun and laughter on a journey that takes them deep into the tiniest of worlds.» For children. Learn more and order your copy online.
Snapshot : Titin
Voulez-vous le taximeter?
Le tionta su la seata
Tu la tu la tu la wa
This is gibberish sung by Charlie Chaplin in ‘Modern Times’ as he struggles to satisfy an impatient audience whilst frantically seeking for his cuff – on which he had written the true lyrics – which had flown off his wrist following an unfortunate flick as he made a hasty entry to perform. He ad-libs novel lyrics to the tune of ‘Je cherche après Titine’ (‘Looking for Titine’) a then popular French song written by M.Bertal and L.Maubon in 1917, the music of which was composed by L.Daniderff. As a result, Chaplin not only added to the song’s popularity but also made it worldwide. Little did he know though that what helped him to dash around the dining-room as he searched for the lost cuff is also named…titin….
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